Juan Lucio Iovanna Selected Research

Nuclear Proteins (Protein, Nuclear)

9/2012	TP53INP1 as new therapeutic target in castration-resistant prostate cancer.
6/2012	Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis.
2/2012	TP53INP1 overexpression in prostate cancer correlates with poor prognostic factors and is predictive of biological cancer relapse.
1/2010	Stress-inducible protein p8 is involved in several physiological and pathological processes.
2/2009	The TP53INP2 protein is required for autophagy in mammalian cells.
12/2006	High level of tumour protein p53-induced nuclear protein 1 (TP53INP1) expression in anaplastic carcinoma of the thyroid.
11/2006	Decreased expression of tumor protein p53-induced nuclear protein 1 (TP53INP1) in breast carcinoma.
2/2006	Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer.
7/2004	Tumor protein p53-induced nuclear protein 1 (TP53INP1) in spontaneous chronic pancreatitis in the WBN/Kob rat: drug effects on its expression in the pancreas.

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Juan Lucio Iovanna Research Topics

Disease

27	Neoplasms (Cancer) 01/2022 - 03/2003
9	Adenocarcinoma 01/2022 - 03/2003
8	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 11/2003
3	Renal Cell Carcinoma (Grawitz Tumor) 11/2020 - 01/2019
3	Melanoma (Melanoma, Malignant) 01/2019 - 01/2013
3	Breast Neoplasms (Breast Cancer) 04/2010 - 03/2005
3	Chronic Pancreatitis 10/2004 - 01/2002
3	Pancreatitis 07/2004 - 03/2003
2	Hypoxia (Hypoxemia) 03/2013 - 01/2009
2	Prostatic Neoplasms (Prostate Cancer) 09/2012 - 02/2012
2	Neoplasm Metastasis (Metastasis) 04/2010 - 01/2010
2	Carcinoma (Carcinomatosis) 12/2006 - 11/2003
2	Thyroid Neoplasms (Thyroid Cancer) 09/2005 - 11/2003
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2022
1	Hepatocellular Carcinoma (Hepatoma) 10/2021
1	Kidney Neoplasms (Kidney Cancer) 10/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019
1	Infections 01/2019
1	Renal Insufficiency (Renal Failure) 01/2017
1	Hypertension (High Blood Pressure) 01/2017
1	Reperfusion Injury 01/2017
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2014
1	Pathologic Processes 01/2010
1	Hypertrophy 01/2010
1	Starvation 02/2009
1	Stomach Neoplasms (Stomach Cancer) 02/2006
1	Inflammation (Inflammations) 02/2004
1	Disease Progression 11/2003
1	Papillary Carcinoma 11/2003

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 04/2021 - 11/2003
9	Nuclear Proteins (Protein, Nuclear)IBA 09/2012 - 07/2004
5	Messenger RNA (mRNA)IBA 09/2012 - 03/2003
4	DNA (Deoxyribonucleic Acid)IBA 08/2014 - 07/2004
3	Pharmaceutical PreparationsIBA 01/2022 - 07/2004
3	Biomarkers (Surrogate Marker)IBA 11/2020 - 01/2019
3	Biological ProductsIBA 11/2020 - 02/2012
3	Pancreatitis-Associated ProteinsIBA 01/2014 - 03/2003
2	NivolumabIBA 11/2020 - 10/2020
2	Oxygen (Dioxygen)IBA 01/2017 - 03/2014
2	Glycoproteins (Glycoprotein)IBA 01/2017 - 03/2013
2	Gemcitabine FDA Link 11/2015 - 06/2008
2	Antisense OligonucleotidesIBA 09/2012 - 02/2012
2	CytokinesIBA 02/2012 - 01/2010
1	IronIBA 01/2022
1	Epithelial Cell Adhesion MoleculeIBA 01/2022
1	salinomycinIBA 01/2022
1	ProdrugsIBA 01/2022
1	1- (4- methylpiperazin- 1- yl)- 3- (5- nitrofuran- 2- yl)prop- 2- en- 1- oneIBA 10/2021
1	Sorafenib (BAY 43-9006)FDA Link 10/2021
1	ButyrophilinsIBA 04/2021
1	LigandsIBA 04/2021
1	MicroRNAs (MicroRNA)IBA 11/2020
1	Immune Checkpoint InhibitorsIBA 10/2020
1	EnzymesIBA 01/2019
1	16S Ribosomal RNAIBA 01/2019
1	ImmunosorbentsIBA 01/2019
1	LectinsIBA 01/2017
1	CollagenIBA 01/2017
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2017
1	Proline (L-Proline)FDA Link 01/2017
1	Lipoproteins (Lipoprotein)IBA 02/2015
1	Small Interfering RNA (siRNA)IBA 02/2015
1	LDL Receptors (LDL Receptor)IBA 02/2015
1	CholesterolIBA 02/2015
1	RNA Helicases (RNA Helicase)IBA 08/2014
1	HexosaminesIBA 03/2013
1	Glutamine (L-Glutamine)FDA Link 03/2013
1	Lactic Acid (Lactate)FDA LinkGeneric 03/2013
1	Mitogen-Activated Protein KinasesIBA 01/2013
1	ThapsigarginIBA 01/2013
1	CalciumIBA 01/2013
1	Phosphotransferases (Kinase)IBA 01/2013
1	VemurafenibIBA 01/2013
1	Proto-Oncogene Proteins B-rafIBA 01/2013
1	AndrogensIBA 09/2012
1	Co-Repressor ProteinsIBA 04/2010
1	Metalloproteases (Metalloproteinases)IBA 01/2010
1	Sirolimus (Rapamycin)FDA Link 02/2009
1	Transcription Factors (Transcription Factor)IBA 01/2009
1	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2008
1	Protein Isoforms (Isoforms)IBA 06/2008
1	Membrane Proteins (Integral Membrane Proteins)IBA 10/2004
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 10/2004
1	Lipase (Acid Lipase)FDA Link 02/2004
1	AntibodiesIBA 02/2004
1	Peroxidase (Myeloperoxidase)IBA 02/2004
1	Amylases FDA Link 02/2004
1	Protease Inhibitors (Protease Inhibitor)IBA 03/2003
1	Peptide Hydrolases (Proteases)FDA Link 03/2003
1	Therapeutic UsesIBA 01/2002
1	IS 741IBA 01/2002

Therapy/Procedure

7	Therapeutics 01/2022 - 01/2009
3	Immunotherapy 11/2020 - 01/2019
3	Drug Therapy (Chemotherapy) 11/2015 - 03/2013
1	Pancreatectomy 11/2015
1	Castration 09/2012
1	Adjuvant Chemotherapy 04/2010